Framinghan heart study

Appraise the Oppenheimer (2010) and Elliott et al. (1999) articles, summarizing the strengths and weaknesses of each study.
Analyze potential sources of bias in each study, and suggest strategies for minimizing bias.
Suggest possible confounding variables that may have influenced the results of each studyAccording to researchers, the strengths of the Framingham has always been their extensive, well characterized , longitudinal phenotype. This study is on its way to becoming the gold standard for genetic epidemiology of CVD.There study was of cohort design. The strength os this study is that it has been one of the longest running most comprehensive characterized multi-generational studies in the world. In addition, other strength of this study is developmental trends across the life span. Most studies of this type is observational in the sense that they observe the state of the participants without manipulation.
The weakness of the study is that a longitudinal study require an enormous amount of time. As time evolve, the research becomes more and more expensive to run and takes up a huge part of a researchers life.
Potential Source of bias and suggested strategies for minimizing bias
The issue of bias in research is an important one and demands special attention. It is important to keep bias out of research. One issue relates to the subjective-objective debate in research. For example, “How do we they keep themselves out when researching a topic that has personal significance?” The way to minimize bias in this situation is try to remain as neutral as possible, It involves open end questions that don’t steer the participants in a way which might appear to endorse a particular response . It involves modeling the interview after conversation between tow trusting parties or individuals. Nevertheless, it is important not to take or impose my interpretation on the comments out of context in order to make a point about bias in research.